Structural Studies of mRNA Vaccines Using Cryogenic Electron Microscopy (cryo-EM) & Scattering

Time: 11:30 am
day: Pre-Conference Focus Day: Deep Dive into mRNA Characterization & Discovery


  • The utility of drugs based on lipid nanoparticles (LNPs) to deliver nucleic acid cargo has been dramatically illustrated by the success of the SARS-CoV-2 mRNA vaccines
  • Many fundamental questions remain about LNP structure/morphology, and particularly how it relates to the quality and efficacy of preparations
  • Presentation of the results of preliminary CryoEM and scattering studies aimed at better understanding the structure and function of LNPs