Thomas Cleveland
Company: National Institute of Standards and Technology, Biomolecular Measurement Division
Job title: Physicist
Seminars:
Panel Discussion: Future Direction of Analytical Capabilities for Better Vaccines 2:30 pm
Are modified protein-based therapeutic assays enough for genetic vaccines, or are we in dire need of the development newer, more modern analytical tools? What are the current gaps in analytical tools to ensure future success of genetic vaccines for infectious diseases and oncology indications? Where will future innovation come from and how must regulation change…Read more
day: Day Two
Structural Studies of mRNA Vaccines Using Cryogenic Electron Microscopy (cryo-EM) & Scattering 11:30 am
The utility of drugs based on lipid nanoparticles (LNPs) to deliver nucleic acid cargo has been dramatically illustrated by the success of the SARS-CoV-2 mRNA vaccines Many fundamental questions remain about LNP structure/morphology, and particularly how it relates to the quality and efficacy of preparations Presentation of the results of preliminary CryoEM and scattering studies…Read more
day: Pre-Conference Focus Day: Deep Dive into mRNA Characterization & Discovery